Gsea fibrosis

Author: ksfq

August undefined, 2024

WebIdiopathic pulmonary fibrosis (IPF) is a progressive disease whose etiology remains unknown. The purpose of this study was to explore hub genes and pathways related to IPF development and prognosis. Multiple gene expression datasets were downloaded from the Gene Expression Omnibus database. Weighted correlation network analysis (WGCNA) … WebJun 17, 2024 · Fibrosis, characterized by fibroblast proliferation and excessive …

Citing GSEA - GSEA MSigDB

WebFibrosis has been classified into two groups: reparative and reactive fibrosis. 9,10 Reparative (replacement) fibrosis or scarring accompanies myocyte death. Reactive fibrosis appears as “interstitial” or “perivascular” … WebFeb 1, 2024 · Notably, HB-EGF has recently been identified as an angiocrine factor that … product tester for scents candles

Type IV collagen α5 chain promotes luminal breast cancer …

WebNational Center for Biotechnology Information WebIn mouse models of skin and lung fibrosis, epiregulin was essential for persistence of fibrosis in both tissues, which could be abrogated by epiregulin genetic deficiency or a neutralizing antibody. WebMar 17, 2024 · Results. A total of 313 DEGs were identified between ICM-HF and normal group of GSE57345, which were mainly enriched in biological processes and pathways related to cell cycle regulation, lipid metabolism pathways, immune response pathways, and intrinsic organelle damage regulation.GSEA results showed positive correlations with … product tester for samsung

Endothelial GATA4 controls liver fibrosis and regeneration …

WebJan 1, 2024 · Rationale: As the central hallmark of liver fibrosis, transdifferentiation of hepatic stellate cells (HSCs), the predominant contributor to fibrogenic hepatic myofibroblast responsible for extracellular matrix (ECM) deposition, is characterized with transcriptional and epigenetic remodeling. We aimed to characterize the roles of H3K27 … WebGOBP_INFLAMMATORY_RESPONSE Human Gene Set: GOBP_INFLAMMATORY_RESPONSE For the Mouse gene set with the same name, see GOBP_INFLAMMATORY_RESPONSE See MSigDB license terms here. reliability philosophyWebFeb 16, 2024 · A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: A prospective derivation and global validation study. reliability physics and engineering cite

"WebDec 7, 2024 · Glycosphingolipids (GSLs), such as the globo-series GSLs stage-specific embryonic antigen 3 (SSEA-3), SSEA-4, and Globo-H, are specifically expressed on pluripotent stem cells and cancer cells, and are … " - Gsea fibrosis

Gsea fibrosis

Positive selection of somatically mutated clones identifies adaptive ...

WebJun 5, 2024 · To identify the gene expression signature of mesothelial cells, we … WebGSEA and MSigDB Need Your Support ... Hepatic fibrosis: Full description or abstract: The presence of excessive fibrous connective tissue in the liver. Fibrosis is a reparative or reactive process. [HPO:probinson] Collection: C5: …

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WebApr 10, 2024 · We observed early fibrosis in the WD-fed livers, indicating that clonal selection occurred in a microenvironment that included pathologic features of NASH ... Finally, GSEA was carried out with the R package fgsea (v1.14.0) using the 'KEGG' and 'Hallmark' libraries from MsigDB. WebJun 17, 2024 · Gene ontology (GO) analysis and Gene Set Enrichment Analysis (GSEA) also suggested that skeletal system development, ossification, and osteoblast associated pathways were enriched in keloid...

WebJun 8, 2024 · Our study revealed the mechanism by which G-MDSCs promote cardiac fibrosis via the secretion of S100A8/A9 and the regulation of FGF2-SOX9 signaling in fibroblasts during aging. ... GSEA indicated ... WebFeb 27, 2006 · Minor to moderate fibrosis was found around the implant attachment point and did not impact ocular function. Serum Antibodies to CNTF and NTC-201 Cells Participant serum samples were collected at preimplantation baseline, at 1, 2, 8, 12, and 24 weeks after implantation, and again 1 month after devices were removed (study week 28).

WebWP_LUNG_FIBROSIS Mouse Gene Set: WP_LUNG_FIBROSIS For the Human gene set with the same name, see WP_LUNG_FIBROSIS See MSigDB license terms here. Please note that certain gene sets have special access terms. WebApr 11, 2024 · Analyses of differentially expressed genes (DEGs), enrichment of gene ontology (GO), the Kyoto Encyclopedia of Genes and Genomes (KEGG), and gene set enrichment analysis (GSEA) were performed. Protein-protein interaction (PPI) network construction was completed by the STRING database.

WebThe fastest growing cause of cancer-related death is hepatocellular carcinoma (HCC), which is at least partly attributable to the rising prevalence of non-alcoholic fatty liver disease. Non-alcoholic fatty liver disease (NAFLD) encompasses a broad spectrum of conditions, ranging from non-progressive bland steatosis to malignant transformation ...

WebNov 15, 2024 · Obesity is a major driver of cancer, especially hepatocellular carcinoma (HCC). The prevailing view is that non-alcoholic steatohepatitis (NASH) and fibrosis or cirrhosis are required for HCC in obesity. Here, we report that NASH and fibrosis and HCC in obesity can be dissociated. We show that the o … product tester for vitamixWebNov 12, 2024 · GSEA refers to either the gene set enrichment analysis or the GSEA … product tester hiring near meWebJun 11, 2024 · GSEA and MSigDB Need Your Support ... HP_CONGENITAL_HEPATIC_FIBROSIS: Systematic name: M35919: Brief description: Congenital hepatic fibrosis: Full description or abstract: The presence of fibrosis of that part of the liver with congenital onset. [HPO:probinson] Collection: reliability physics and engineering pdfWebApr 10, 2024 · We recently reported that DT-109 administered orally to mice at 500 mg/kg/day potently reduced steatohepatitis and fibrosis induced by a high-fat, -fructose, and -cholesterol diet (NASH diet). 13 To determine optimal dosing, we evaluated the dose response of DT-109 during NASH. C57BL/6J mice were fed the NASH diet for 12 weeks … reliability phrases for reviewsWebApr 17, 2024 · Idiopathic Pulmonary Fibrosis (IPF) is one of the most common idiopathic interstitial pneumonia, which can occur all over the world. The median survival time of patients is about 3-5 years, and the mortality is relatively high. Objective . ... GSEA revealed that subgroup-specific upregulated genes were also significantly upregulated in case ... product tester hub review reliability physicsWeb2 days ago · We defined chronic liver disease as the development of liver fibrosis or cirrhosis, combining the following ICD10 diagnostic codes: K70.2 (alcoholic fibrosis and sclerosis of the liver), K70.3 ... product tester get free stuff