Web• lack of appetite • discomfort on the right upper corner of the abdomen • generalized itching • dark urine and jaundice (yellow discoloration of the eyes and skin) • many people have no symptoms at all. Diagnosis Blood tests can usually detect evidence of liver damage before symptoms develop. WebCumulative Effect of Drugs 1. The Too Frequent Administration of a drug which is slow of excretion will cause it to accumulate in the sys tern, and... 2. Cumulative Action From …
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Webcumulative drug action The action of repeated doses of drugs that are not immediately eliminated from the body. For example, preparations containing lead, silver, and mercury tend to accumulate in the body and gradually produce symptoms of poisoning. See also: action Medical Dictionary, © 2009 Farlex and Partners WebIncreasing the dose of a drug with a small therapeutic index increases the probability of toxicity or ineffectiveness of the drug. However, these features differ by population and are affected by patient-related factors, such as pregnancy , age , and organ function (eg, estimated GFR ). WebApr 11, 2024 · Lifetime cumulative doses of Adriamycin above 550 mg/m2 (for 21-day cycles) are associated with an increased risk of cardiomyopathy. In people at high risk of … simply home furnishings midland