Crystalluria acyclovir
WebFor decades, acyclovir-induced nephrotoxicity was believed to be secondary to crystalluria. Clinical evidence of nephrotoxicity in the absence of crystalluria suggests that acyclovir …
Crystalluria acyclovir
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WebAcyclovir is filtered by glomeruli and secreted in renal tubules producing high tubular concentrations. It is relatively insoluble in urine. Intra-tubular crystals obstruct the nephron leading to acute renal failure. Crystalluria usually … WebOf 19 children treated with high-dose intravenous acyclovir, 7, all of whom had encephalitis, also had a restricted fluid intake. Of these, 3 experienced nonoliguric renal insufficiency (plasma creatinine up to 176, 250 and 351 μmol/l, respectively) which resolved within 1 week of discontinuing acyclovir. Renal function was stable in the remaining 4 patients in …
WebAcyclovir crystalluria is considered a rare adverse effect which is more commonly described if there is intravenous administration. However, it may also be associated with oral administration [9]. It is more common in immunosuppressed patients, probably due … WebApr 1, 2008 · One of the mechanisms for acyclovir-induced nephrotoxicity is acyclovir-induced crystalluria. Prompt attention to urine microscopy examination can help avoid drug-induced nephrotoxicity.
WebJan 1, 2016 · Acyclovir is a highly active antiviral drug that acts against the herpes simplex virus (HSV). Among its secondary effects, we can observe rare cases of crystalluria, which can be associated or not ... WebAcyclovir crystals may precipitate in the renal tubules, particularly when the drug is injected intravenously as a bolus. Abnormal renal function may occur, which is usually reversible but may infrequently progress to tubular damage and acute renal failure.
WebMar 9, 2010 · Acyclovir is commonly used in transplant patients, herpes virus, and varicella zoster virus infections, and other patients who present with potential viral CNS infections; hence, clinicians must be familiar with …
WebSep 14, 2024 · One of the mechanisms for acyclovir-induced nephrotoxicity is acyclovir-induced crystalluria. Prompt attention to urine microscopy examination can help avoid … simple everyday makeup for brown skinWebApr 8, 2024 · INTRODUCTION. Crystal-induced acute kidney injury (AKI) is caused by the intratubular precipitation of crystals, which results in obstruction. Crystal-induced AKI … simpleeverydaymom grinchWebAcyclovir is widely used to treat herpes virus infections, particularly those associated with herpes simplex virus and varicella-zoster virus. Randomized controlled trials have shown that acyclovir effectively reduces the duration and severity of painful lesions, prevents complications, and decreases recurrence . simple everyday makeup for schoolWebCrystalluria is usually clinically insignificant, but can be important in limited situations. Crystal type is important in association with current or prior occurrence of calculi and when one suspects a portosystemic shunt, ethylene glycol toxicity (Figure 7-7 ), or melamine intoxication. Whenever crystalluria is considered significant, it is ... simple everyday makeup tutorial for beginnerWebJun 1, 2002 · First, acyclovir crystalluria is a rare side effect of a very commonly used drug. While there are few published reports that specifically describe this crystalluria, … simple everyday mom reindeer headbandWebJul 15, 2012 · Drug-induced nephrotoxicity appears to be attributed to renal tubular damage caused by acyclovir-induced crystalluria (Pathol Lab Med. 2002;126:753-754). Topical acyclovir is available by ... rawhide incident of the day of the deadWebJul 1, 2002 · The acyclovir can cause crystalluria though it is an uncommon side effect of commonly used drugs. [7] The occurrence of acyclovir-induced crystalluria increases when high dosages are given... rawhide incident of the dog days cast